Targeted sequencing of circulating cell-free DNA (cfDNA) is used in routine clinical diagnostics for the identification of predictive biomarkers in cancer patients in an advanced stage.The presence of KRAS mutations associated with clonal hematopoiesis of indeterminate potential (CHIP) might represent a confounding factor.We used an amplicon-based
Objective: To evaluate the toxicological and psychotropic properties of Calotropis (C.) procera.Methods: C.procera leaves and root-bark aqueous extracts were evaluated for their toxic and behavioral effects using adult mice.Toxicity studies were carried out using Organisation for Economic Cooperation and Development guidelines 423 and 407 for acute
In this study, we propose a more comprehensive and realistic option pricing model based on approximative fractional Brownian motion, building upon recent advancements in this area.Specifically, we utilize the double 3/2-volatility Jump-Diffusion model, which incorporates approximative fractional Brownian motion with 3/2-volatility, stochastic inter
Spyridon FortisDepartment of Medicine, Division of Pulmonary, Critical Care and Occupational Medicine, University of Iowa, Iowa City, IA, USAAirflow obstruction or obstructive ventilatory defect (OVD) is defined as low forced expiratory volume in 1 second (FEV1) to vital capacity (VC) ratio.VC can be measured in massagers-small various ways, and th